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Sign

Pyoderma gangrenosum

A rare inflammatory skin disorder that can cause rapidly enlarging, painful ulcers, including in people with inflammatory bowel disease.

Found
Usually on the lower legs; ulcers may also develop around a stoma.
Normal
No rapidly enlarging, painful ulcer with a violaceous, undermined edge.
Abnormal
A rapidly enlarging, very painful ulcer, often with a violaceous, undermined border.
Suggests
Pyoderma gangrenosum; it is associated with inflammatory bowel disease.
Exceptions
The bowel disease may be mild, and skin activity does not always parallel intestinal activity.

Pyoderma gangrenosum is an inflammatory skin condition rather than an infection. It may appear as an extraintestinal finding in a child with inflammatory bowel disease. Its painful, expanding ulcers can draw attention to the association even when bowel symptoms do not reflect the skin disease. It can also occur without inflammatory bowel disease.

Card id: pyoderma-gangrenosum

Sources

  • Zaino ML, Schadt CR, Callen JP, Owen LG. Pyoderma Gangrenosum: Diagnostic Criteria, Subtypes, Systemic Associations, and Workup. Dermatologic Clinics, 2024, https://pubmed.ncbi.nlm.nih.gov/38423678/

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