Word
Myeloid neoplasm post cytotoxic therapy
In WHO-HAEM5, prior cytotoxic therapy is recorded as a qualifier on a myeloid neoplasm, not as a separate disease.
Also called: Therapy-related myeloid neoplasms
This is a myeloid malignancy that arises after cytotoxic treatment given for another disease. WHO-HAEM5 no longer treats it as a separate disease; it adds the qualifier post cytotoxic therapy to a specific diagnosis such as acute myeloid leukemia, myelodysplastic neoplasm, or MDS/MPN. The International Consensus Classification keeps the older therapy-related wording. Knowing the prior treatment matters clinically without replacing the diagnosis of the underlying myeloid disease.